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140
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BMCBI
2005
15 years 3 months ago
2005
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
139
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BMCBI
2005
15 years 3 months ago
2005
Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
124
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BMCBI
2005
15 years 3 months ago
2005
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
142
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JCB
2007
15 years 3 months ago
2007
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
171
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TOSEM
2008
15 years 3 months ago
2008
Modern programs make extensive use of reusable software libraries. For example, a study of a number of large Java applications shows that between 17% and 30% of the classes in tho...