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BMCBI
2008
13 years 7 months ago
2008
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
BMCBI
2007
13 years 7 months ago
2007
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
BMCBI
2008
13 years 7 months ago
2008
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
BMCBI
2007
13 years 7 months ago
2007
Background: Most single stranded RNA (ssRNA) viruses mutate rapidly to generate large number of strains having highly divergent capsid sequences. Accurate strain recognition in un...
BMCBI
2010
13 years 7 months ago
2010
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...