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BMCBI
2010
137views more  BMCBI 2010»
13 years 7 months ago
TassDB2 - A comprehensive database of subtle alternative splicing events
Background: Subtle alternative splicing events involving tandem splice sites separated by a short (2-12 nucleotides) distance are frequent and evolutionarily widespread in eukaryo...
Rileen Sinha, Thorsten Lenser, Niels Jahn, Ulrike ...
BMCBI
2010
99views more  BMCBI 2010»
13 years 7 months ago
A statistical method for excluding non-variable CpG sites in high-throughput DNA methylation profiling
Background: High-throughput DNA methylation arrays are likely to accelerate the pace of methylation biomarker discovery for a wide variety of diseases. A potential problem with a ...
Hailong Meng, Andrew R. Joyce, Daniel E. Adkins, P...
BMCBI
2006
123views more  BMCBI 2006»
13 years 7 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
BMCBI
2006
184views more  BMCBI 2006»
13 years 7 months ago
PubFocus: semantic MEDLINE/PubMed citations analytics through integration of controlled biomedical dictionaries and ranking algo
Background: Understanding research activity within any given biomedical field is important. Search outputs generated by MEDLINE/PubMed are not well classified and require lengthy ...
Maksim V. Plikus, Zina Zhang, Cheng-Ming Chuong
BMCBI
2007
131views more  BMCBI 2007»
13 years 7 months ago
ISHAPE: new rapid and accurate software for haplotyping
Background: We have developed a new haplotyping program based on the combination of an iterative multiallelic EM algorithm (IEM), bootstrap resampling and a pseudo Gibbs sampler. ...
Olivier Delaneau, Cédric Coulonges, Pierre-...