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BMCBI
2010
160views more  BMCBI 2010»
13 years 10 months ago
Annotation of gene promoters by integrative data-mining of ChIP-seq Pol-II enrichment data
Background: Use of alternative gene promoters that drive widespread cell-type, tissue-type or developmental gene regulation in mammalian genomes is a common phenomenon. Chromatin ...
Ravi Gupta, Priyankara Wikramasinghe, Anirban Bhat...
JIB
2007
75views more  JIB 2007»
13 years 10 months ago
Mapping protein information to disease terminologies
In order to improve the accessibility of genomic and proteomic information to medical researchers, we have developed a procedure to link biological information on proteins involve...
Anaïs Mottaz, Yum Lina Yip, Patrick Ruch, Ann...
RECOMB
2002
Springer
14 years 10 months ago
A Survey of Computational Methods for Determining Haplotypes
It is widely anticipated that the study of variation in the human genome will provide a means of predicting risk of a variety of complex diseases. Single nucleotide polymorphisms (...
Bjarni V. Halldórsson, Vineet Bafna, Nathan...
RECOMB
2008
Springer
14 years 10 months ago
Reconstructing the Evolutionary History of Complex Human Gene Clusters
Abstract. Clusters of genes that evolved from single progenitors via repeated segmental duplications present significant challenges to the generation of a truly complete human geno...
Adam C. Siepel, Eric D. Green, Giltae Song, Tom&aa...
SIGIR
2005
ACM
14 years 3 months ago
An application of text categorization methods to gene ontology annotation
This paper describes an application of IR and text categorization methods to a highly practical problem in biomedicine, specifically, Gene Ontology (GO) annotation. GO annotation...
Kazuhiro Seki, Javed Mostafa