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176
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BMCBI
2007
2007
Penalized likelihood for sparse contingency tables with an application to full-length cDNA libraries
15 years 6 months ago
Background: The joint analysis of several categorical variables is a common task in many areas of biology, and is becoming central to systems biology investigations whose goal is ...
148
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BMCBI
2007
15 years 6 months ago
2007
Background: The translation start site plays an important role in the control of translation efficiency of eukaryotic mRNAs. The recognition of the start AUG codon by eukaryotic r...
145
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BMCBI
2010
15 years 6 months ago
2010
Background: PDZ domains mediate protein-protein interactions involved in important biological processes through the recognition of short linear motifs in their target proteins. Tw...
131
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BMCBI
2008
15 years 6 months ago
2008
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
187
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BMCBI
2006
15 years 6 months ago
2006
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...