Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Background: Advances in DNA microarray technology portend that molecular signatures from which microarray will eventually be used in clinical environments and personalized medicin...
Zhenqiang Su, Huixiao Hong, Hong Fang, Leming M. S...
We present a novel approach to parameterize a mesh with disk topology to the plane in a shape-preserving manner. Our key contribution is a local/global algorithm, which combines a...
Ligang Liu, Lei Zhang, Yin Xu, Craig Gotsman, Stev...
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
Background: Microarray technologies have become common tools in biological research. As a result, a need for effective computational methods for data analysis has emerged. Numerou...