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JIB
2006
110views more  JIB 2006»
13 years 8 months ago
Combining biomedical knowledge and transcriptomic data to extract new knowledge on genes
In biomedical research, interpretation of microarray data requires confrontation of data and knowledge from heterogeneous resources, either in the biomedical domain or in genomics...
Emilie Guérin, Gwenaëlle Marquet, Juli...
BMCBI
2010
160views more  BMCBI 2010»
13 years 8 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
PR
2008
88views more  PR 2008»
13 years 8 months ago
Modified global k
Clustering in gene expression data sets is a challenging problem. Different algorithms for clustering of genes have been proposed. However due to the large number of genes only a ...
Adil M. Bagirov
BMCBI
2006
119views more  BMCBI 2006»
13 years 8 months ago
Evaluation of microarray data normalization procedures using spike-in experiments
Background: Recently, a large number of methods for the analysis of microarray data have been proposed but there are few comparisons of their relative performances. By using so-ca...
Patrik Rydén, Henrik Andersson, Mattias Lan...
BMCBI
2007
147views more  BMCBI 2007»
13 years 8 months ago
Statistical analysis and significance testing of serial analysis of gene expression data using a Poisson mixture model
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...
Scott D. Zuyderduyn