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BMCBI
2005
114views more  BMCBI 2005»
13 years 7 months ago
Quality determination and the repair of poor quality spots in array experiments
Background: A common feature of microarray experiments is the occurence of missing gene expression data. These missing values occur for a variety of reasons, in particular, becaus...
Brian D. M. Tom, Walter R. Gilks, Elizabeth T. Bro...
BMCBI
2008
78views more  BMCBI 2008»
13 years 8 months ago
Evaluation of time profile reconstruction from complex two-color microarray designs
Background: As an alternative to the frequently used "reference design" for two-channel microarrays, other designs have been proposed. These designs have been shown to b...
Ana C. Fierro, Raphael Thuret, Kristof Engelen, Gi...
BMCBI
2004
94views more  BMCBI 2004»
13 years 7 months ago
The tissue microarray data exchange specification: implementation by the Cooperative Prostate Cancer Tissue Resource
Background: Tissue Microarrays (TMAs) have emerged as a powerful tool for examining the distribution of marker molecules in hundreds of different tissues displayed on a single sli...
Jules J. Berman, Milton Datta, Andre Kajdacsy-Ball...
BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
An algorithm for automatic evaluation of the spot quality in two-color DNA microarray experiments
Background: Although DNA microarray technologies are very powerful for the simultaneous quantitative characterization of thousands of genes, the quality of the obtained experiment...
Eugene Novikov, Emmanuel Barillot
BMCBI
2010
156views more  BMCBI 2010»
13 years 8 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...