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BMCBI
2007
133views more  BMCBI 2007»
13 years 8 months ago
GenMAPP 2: new features and resources for pathway analysis
Background: Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence variations for ...
Nathan Salomonis, Kristina Hanspers, Alexander C. ...
BMCBI
2006
108views more  BMCBI 2006»
13 years 8 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman
BMCBI
2010
155views more  BMCBI 2010»
13 years 8 months ago
A flexible R package for nonnegative matrix factorization
Background: Nonnegative Matrix Factorization (NMF) is an unsupervised learning technique that has been applied successfully in several fields, including signal processing, face re...
Renaud Gaujoux, Cathal Seoighe
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
14 years 1 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
ICDE
2003
IEEE
149views Database» more  ICDE 2003»
14 years 9 months ago
Indexing Weighted-Sequences in Large Databases
We present an index structure for managing weightedsequences in large databases. A weighted-sequence is defined as a two-dimensional structure where each element in the sequence i...
Haixun Wang, Chang-Shing Perng, Wei Fan, Sanghyun ...