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BMCBI
2011
12 years 11 months ago
Cell Subset Prediction for Blood Genomic Studies
Background: Genome-wide transcriptional profiling of patient blood samples offers a powerful tool to investigate underlying disease mechanisms and personalized treatment decisions...
Christopher R. Bolen, Mohamed Uduman, Steven H. Kl...
RECOMB
2009
Springer
14 years 8 months ago
Evaluating Between-Pathway Models with Expression Data
Abstract. Between-Pathway Models (BPMs) are network motifs consisting of pairs of putative redundant pathways. In this paper, we show how adding another source of high-throughput d...
Benjamin J. Hescott, Mark D. M. Leiserson, Lenore ...
BMCBI
2006
125views more  BMCBI 2006»
13 years 8 months ago
Evaluating different methods of microarray data normalization
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
André Fujita, João Ricardo Sato, Leo...
EVOW
2005
Springer
14 years 1 months ago
Order Preserving Clustering over Multiple Time Course Experiments
Abstract. Clustering still represents the most commonly used technique to analyze gene expression data—be it classical clustering approaches that aim at finding biologically rel...
Stefan Bleuler, Eckart Zitzler
BMCBI
2004
117views more  BMCBI 2004»
13 years 8 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...