The UCSC Cancer Genomics Browser (https:// genome-cancer.ucsc.edu) comprises a suite of web-based tools to integrate, visualize and analyze cancer genomics and clinical data. The ...
J. Zachary Sanborn, Stephen C. Benz, Brian Craft, ...
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
Background: Systematic evaluation and study of single nucleotide polymorphisms (SNPs) made possible by high throughput genotyping technologies and bioinformatics promises to provi...
Qian Xie, Luke D. Ratnasinghe, Huixiao Hong, Roger...
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...