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BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
Visualization-based discovery and analysis of genomic aberrations in microarray data
Background: Chromosomal copy number changes (aneuploidies) play a key role in cancer progression and molecular evolution. These copy number changes can be studied using microarray...
Chad L. Myers, Xing Chen, Olga G. Troyanskaya
EVOW
2003
Springer
14 years 21 days ago
Chromosomal Breakpoint Detection in Human Cancer
Chromosomal aberrations are differences in DNA sequence copy number of chromosome regions 3 . These differences may be crucial genetic events in the development and progression o...
Kees Jong, Elena Marchiori, Aad van der Vaart, Bau...
CIKM
2009
Springer
14 years 2 months ago
Multivariate classification of urine metabolome profiles for breast cancer diagnosis
Background: Diagnosis techniques using urine are non-invasive, inexpensive, and easy to perform in clinical settings. The metabolites in urine, as the end products of cellular pro...
Younghoon Kim, Imhoi Koo, Byung Hwa Jung, Bong Chu...
BMCBI
2002
195views more  BMCBI 2002»
13 years 7 months ago
Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study
Background: A method to evaluate and analyze the massive data generated by series of microarray experiments is of utmost importance to reveal the hidden patterns of gene expressio...
Junbai Wang, Jan Delabie, Hans Christian Aasheim, ...
RECOMB
2008
Springer
14 years 7 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir