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BMCBI
2011
12 years 11 months ago
RegNetB: Predicting Relevant Regulator-Gene Relationships in Localized Prostate Tumor Samples
Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Angel Alvarez, Peter J. Woolf
BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...
BMCBI
2011
13 years 2 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
RECOMB
2004
Springer
14 years 7 months ago
Comparing in situ mRNA expression patterns of drosophila embryos
In situ staining of a target mRNA at several time points during the development of a D. melanogaster embryo gives one a detailed spatio-temporal view of the expression pattern of ...
Hanchuan Peng, Eugene W. Myers
BMCBI
2008
128views more  BMCBI 2008»
13 years 7 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...