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» Identifying Projected Clusters from Gene Expression Profiles
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BMCBI
2006
119views more  BMCBI 2006»
13 years 8 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2008
164views more  BMCBI 2008»
13 years 9 months ago
MeInfoText: associated gene methylation and cancer information from text mining
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
Yu-Ching Fang, Hsuan-Cheng Huang, Hsueh-Fen Juan
ICDE
2004
IEEE
133views Database» more  ICDE 2004»
14 years 10 months ago
GenExplore: Interactive Exploration of Gene Interactions from Microarray Data
DNA Microarray provides a powerful basis for analysis of gene expression. Data mining methods such as clustering have been widely applied to microarray data to link genes that sho...
Yong Ye, Xintao Wu, Kalpathi R. Subramanian, Liyin...
BMCBI
2007
151views more  BMCBI 2007»
13 years 9 months ago
A statistical method to incorporate biological knowledge for generating testable novel gene regulatory interactions from microar
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
Peter Larsen, Eyad Almasri, Guanrao Chen, Yang Dai
BMCBI
2007
120views more  BMCBI 2007»
13 years 8 months ago
Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: High-resolution annotation for microarrays
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...