Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
DNA Microarray provides a powerful basis for analysis of gene expression. Data mining methods such as clustering have been widely applied to microarray data to link genes that sho...
Yong Ye, Xintao Wu, Kalpathi R. Subramanian, Liyin...
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
Peter Larsen, Eyad Almasri, Guanrao Chen, Yang Dai
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...