Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...
The DBAli tools use a comprehensive set of structural alignments in the DBAli database to leverage the structural information deposited in the Protein Data Bank (PDB). These tools...
Background: Currently there is a strong need for methods that help to obtain an accurate description of protein interfaces in order to be able to understand the principles that go...
Joan Teyra, Andreas Doms, Michael Schroeder, M. Te...
A genetic algorithm (GA) is utilised to discover known and novel PROSITE-like sequence templates that can be used to classify the sub-cellular location of eukaryotic proteins. Whi...
Background: Identification of the structural domains of proteins is important for our understanding of the organizational principles and mechanisms of protein folding, and for ins...