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» Identifying Structural Motifs in Proteins
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BMCBI
2010
156views more  BMCBI 2010»
13 years 10 months ago
Protein complex prediction via verifying and reconstructing the topology of domain-domain interactions
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
Yosuke Ozawa, Rintaro Saito, Shigeo Fujimori, Hisa...
BMCBI
2007
128views more  BMCBI 2007»
13 years 10 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BMCBI
2008
114views more  BMCBI 2008»
13 years 10 months ago
Indel PDB: A database of structural insertions and deletions derived from sequence alignments of closely related proteins
Background: Insertions and deletions (indels) represent a common type of sequence variations, which are less studied and pose many important biological questions. Recent research ...
Michael Hsing, Artem Cherkasov
ENGL
2008
121views more  ENGL 2008»
13 years 10 months ago
Prediction of Protein-Protein Interactions Using Pairwise Alignment and Inter-Domain Linker Region
One of the central problems in modern biology is to identify the complete set of interactions among the proteins in a cell. The structural interaction of proteins and their domains...
Nazar Zaki
BMCBI
2010
132views more  BMCBI 2010»
13 years 10 months ago
An interaction-motif-based scoring function for protein-ligand docking
Background: A good scoring function is essential for molecular docking computations. In conventional scoring functions, energy terms modeling pairwise interactions are cumulativel...
Zhong-Ru Xie, Ming-Jing Hwang