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» Identifying Structural Motifs in Proteins
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BMCBI
2006
133views more  BMCBI 2006»
13 years 10 months ago
Choosing negative examples for the prediction of protein-protein interactions
The protein-protein interaction networks of even well-studied model organisms are sketchy at best, highlighting the continued need for computational methods to help direct experim...
Asa Ben-Hur, William Stafford Noble
BIOINFORMATICS
2000
149views more  BIOINFORMATICS 2000»
13 years 9 months ago
MaxSub: an automated measure for the assessment of protein structure prediction quality
Motivation: Evaluating the accuracy of predicted models is critical for assessing structure prediction methods. Because this problem is not trivial, a large number of different as...
Naomi Siew, Arne Elofsson, Leszek Rychlewski, Dani...
BMCBI
2008
133views more  BMCBI 2008»
13 years 10 months ago
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...
JCB
2000
90views more  JCB 2000»
13 years 9 months ago
Geometric Invariant Core for the CL and CH1 Domains of Immunoglobulin Molecules
A previously developed algorithmic method for identifying a geometric invariant of protein structures, termed geometrical core, is extended to the and 1 domains of immunoglobulin ...
Ognyan Stoyanov, Alexander Kister, Israel Gelfand,...
BMCBI
2007
175views more  BMCBI 2007»
13 years 10 months ago
CLUSS: Clustering of protein sequences based on a new similarity measure
Background: The rapid burgeoning of available protein data makes the use of clustering within families of proteins increasingly important. The challenge is to identify subfamilies...
Abdellali Kelil, Shengrui Wang, Ryszard Brzezinski...