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BMCBI
2005
124views more  BMCBI 2005»
13 years 6 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2005
120views more  BMCBI 2005»
13 years 6 months ago
Harshlight: a "corrective make-up" program for microarray chips
Background: Microscopists are familiar with many blemishes that fluorescence images can have due to dust and debris, glass flaws, uneven distribution of fluids or surface coatings...
Mayte Suárez-Fariñas, Maurizio Pelle...
BMCBI
2005
98views more  BMCBI 2005»
13 years 6 months ago
DCD - a novel plant specific domain in proteins involved in development and programmed cell death
Background: Recognition of microbial pathogens by plants triggers the hypersensitive reaction, a common form of programmed cell death in plants. These dying cells generate signals...
Raimund Tenhaken, Tobias Doerks, Peer Bork
BMCBI
2005
105views more  BMCBI 2005»
13 years 6 months ago
Secondary structure assignment that accurately reflects physical and evolutionary characteristics
Background: Secondary structure is used in hierarchical classification of protein structures, identification of protein features, such as helix caps and loops, for fold recognitio...
Maria Vittoria Cubellis, Fabien Cailliez, Simon C....
BMCBI
2004
93views more  BMCBI 2004»
13 years 6 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...