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    BMCBI
    2007
    147views more  BMCBI 2007»
    Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
    13 years 8 months ago
    Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
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    Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
    Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...
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    BMCBI
    2008
    135views more  BMCBI 2008»
    Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
    13 years 8 months ago
    Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
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    Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
    Hailong Meng, Edward Lenn Murrelle, Guoya Li
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    BMCBI
    2008
    126views more  BMCBI 2008»
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
    13 years 8 months ago
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
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    Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
    Katerina Kechris, Hao Li
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    BMCBI
    2006
    103views more  BMCBI 2006»
    Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
    13 years 8 months ago
    Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
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    Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
    Sébastien Lemieux
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    JMLR
    2008
    127views more  JMLR 2008»
    Incremental Identification of Qualitative Models of Biological Systems using Inductive Logic Programming
    13 years 8 months ago
    Incremental Identification of Qualitative Models of Biological Systems using Inductive Logic Programming
    Download  jmlr.csail.mit.edu
    The use of computational models is increasingly expected to play an important role in predicting the behaviour of biological systems. Models are being sought at different scales o...
    Ashwin Srinivasan, Ross D. King
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