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» Identifying enrichment candidates in textbooks
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BMCBI
2010
101views more  BMCBI 2010»
13 years 11 months ago
Enrichment of homologs in insignificant BLAST hits by co-complex network alignment
Background: Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stri...
Like Fokkens, Sandra M. C. Botelho, Jos Boekhorst,...
COMPUTER
2006
84views more  COMPUTER 2006»
13 years 11 months ago
Testable, Reusable Units of Cognition
The educational content of a technical topic consists, ultimately, of elementary chunks of knowledge. Identifying and classifying such units -- Testable, Reusable Units of Cogniti...
Bertrand Meyer
BMCBI
2007
112views more  BMCBI 2007»
13 years 11 months ago
Inferring biological functions and associated transcriptional regulators using gene set expression coherence analysis
Background: Gene clustering has been widely used to group genes with similar expression pattern in microarray data analysis. Subsequent enrichment analysis using predefined gene s...
Tae-Min Kim, Yeun-Jun Chung, Mun-Gan Rhyu, Myeong ...
BMCBI
2010
125views more  BMCBI 2010»
13 years 11 months ago
A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins
Background: Several bioinformatic approaches have previously been used to find novel sites of ADAR mediated A-to-I RNA editing in human. These studies have discovered thousands of...
Mats Ensterö, Örjan Åkerborg, Dani...
BMCBI
2008
202views more  BMCBI 2008»
13 years 11 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...