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BMCBI
2005
124views more  BMCBI 2005»
13 years 7 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
Functional clustering of yeast proteins from the protein-protein interaction network
Background: The abundant data available for protein interaction networks have not yet been fully understood. New types of analyses are needed to reveal organizational principles o...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
CEC
2010
IEEE
13 years 8 months ago
Evolutionary layered hypernetworks for identifying microRNA-mRNA regulatory modules
Abstract-- Exploring microRNA (miRNA) and mRNA regulatory interactions may give new insights into diverse biological phenomena. While elucidating complex miRNA-mRNA interactions ha...
Soo-Jin Kim, JungWoo Ha, Bado Lee, Byoung-Tak Zhan...
BMCBI
2005
116views more  BMCBI 2005»
13 years 7 months ago
Dynamic covariation between gene expression and proteome characteristics
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
Mansour Taghavi Azar Sharabiani, Markku Siermala, ...
BMCBI
2010
100views more  BMCBI 2010»
13 years 7 months ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...