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NIPS
1997
13 years 8 months ago
Computing with Action Potentials
Most computational engineering based loosely on biology uses continuous variables to represent neural activity. Yet most neurons communicate with action potentials. The engineerin...
John J. Hopfield, Carlos D. Brody, Sam T. Roweis
BMCBI
2010
154views more  BMCBI 2010»
13 years 7 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2010
129views more  BMCBI 2010»
13 years 7 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
BIOSYSTEMS
2008
107views more  BIOSYSTEMS 2008»
13 years 7 months ago
The linearity of emergent spectro-temporal receptive fields in a model of auditory cortex
The responses of cortical neurons are often characterized by measuring their spectro-temporal receptive fields (strfs). The strf of a cell can be thought of as a representation of...
Martin Coath, Emili Balaguer-Ballester, Sue L. Den...
BMCBI
2007
91views more  BMCBI 2007»
13 years 7 months ago
A machine learning approach for the identification of odorant binding proteins from sequence-derived properties
Background: Odorant binding proteins (OBPs) are believed to shuttle odorants from the environment to the underlying odorant receptors, for which they could potentially serve as od...
Ganesan Pugalenthi, E. Ke Tang, Ponnuthurai N. Sug...