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» Impact of RNA structure on the prediction of donor and accep...
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BMCBI
2006
114views more  BMCBI 2006»
13 years 8 months ago
Impact of RNA structure on the prediction of donor and acceptor splice sites
Background: gene identification in genomic DNA sequences by computational methods has become an important task in bioinformatics and computational gene prediction tools are now es...
Sayed-Amir Marashi, Changiz Eslahchi, Hamid Pezesh...
BMCBI
2007
96views more  BMCBI 2007»
13 years 8 months ago
Features generated for computational splice-site prediction correspond to functional elements
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...
BMCBI
2010
103views more  BMCBI 2010»
13 years 8 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
ICDM
2002
IEEE
173views Data Mining» more  ICDM 2002»
14 years 1 months ago
Mining Genes in DNA Using GeneScout
In this paper, we present a new system, called GeneScout, for predicting gene structures in vertebrate genomic DNA. The system contains specially designed hidden Markov models (HM...
Michael M. Yin, Jason Tsong-Li Wang
BMCBI
2008
102views more  BMCBI 2008»
13 years 8 months ago
Fast splice site detection using information content and feature reduction
Background: Accurate identification of splice sites in DNA sequences plays a key role in the prediction of gene structure in eukaryotes. Already many computational methods have be...
A. K. M. A. Baten, Saman K. Halgamuge, Bill C. H. ...