Background: The goal of most microarray studies is either the identification of genes that are most differentially expressed or the creation of a good classification rule. The dis...
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
One of the most important, common and critical management issues lies in determining the "best" project portfolio out of a given set of investment proposals. As this dec...
Karl F. Doerner, Walter J. Gutjahr, Richard F. Har...
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...