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BMCBI
2010
124views more  BMCBI 2010»
13 years 7 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2007
112views more  BMCBI 2007»
13 years 7 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
BMCBI
2008
124views more  BMCBI 2008»
13 years 7 months ago
Ontology-based, Tissue MicroArray oriented, image centered tissue bank
Background: Tissue MicroArray technique is becoming increasingly important in pathology for the validation of experimental data from transcriptomic analysis. This approach produce...
Federica Viti, Ivan Merelli, Andrea Caprera, Barba...
BMCBI
2006
111views more  BMCBI 2006»
13 years 7 months ago
SIMMAP: Stochastic character mapping of discrete traits on phylogenies
Background: Character mapping on phylogenies has played an important, if not critical role, in our understanding of molecular, morphological, and behavioral evolution. Until very ...
Jonathan P. Bollback
BMCBI
2006
131views more  BMCBI 2006»
13 years 7 months ago
SIMAGE: simulation of DNA-microarray gene expression data
Background: Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-proce...
Casper J. Albers, Ritsert C. Jansen, Jan Kok, Osca...