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» Improved Decomposition of STGs
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BMCBI
2008
95views more  BMCBI 2008»
13 years 10 months ago
Unsupervised reduction of random noise in complex data by a row-specific, sorted principal component-guided method
Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
Joseph W. Foley, Fumiaki Katagiri
BMCBI
2007
135views more  BMCBI 2007»
13 years 10 months ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
BMCBI
2008
112views more  BMCBI 2008»
13 years 10 months ago
A simplified approach to disulfide connectivity prediction from protein sequences
Background: Prediction of disulfide bridges from protein sequences is useful for characterizing structural and functional properties of proteins. Several methods based on differen...
Marc Vincent, Andrea Passerini, Matthieu Labb&eacu...
BMCBI
2008
138views more  BMCBI 2008»
13 years 10 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...
CORR
2010
Springer
190views Education» more  CORR 2010»
13 years 10 months ago
Bidimensionality and EPTAS
Bidimensionality theory appears to be a powerful framework for the development of metaalgorithmic techniques. It was introduced by Demaine et al. [J. ACM 2005 ] as a tool to obtai...
Fedor V. Fomin, Daniel Lokshtanov, Venkatesh Raman...