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BMCBI
2007
91views more  BMCBI 2007»
13 years 10 months ago
A mass accuracy sensitive probability based scoring algorithm for database searching of tandem mass spectrometry data
Background: Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) has become one of the most used tools in mass spectrometry based proteomics. Various algorithms ...
Hua Xu, Michael A. Freitas
BMCBI
2010
139views more  BMCBI 2010»
13 years 10 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
BMCBI
2008
159views more  BMCBI 2008»
13 years 10 months ago
Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng, Hong...
BMCBI
2006
116views more  BMCBI 2006»
13 years 9 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
CORR
2007
Springer
95views Education» more  CORR 2007»
13 years 9 months ago
Scheduling in Data Intensive and Network Aware (DIANA) Grid Environments
In Grids scheduling decisions are often made on the basis of jobs being either data or computation intensive: in data intensive situations jobs may be pushed to the data and in co...
Richard McClatchey, Ashiq Anjum, Heinz Stockinger,...