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BMCBI
2007
117views more  BMCBI 2007»
15 years 2 months ago
Meta-analysis of several gene lists for distinct types of cancer: A simple way to reveal common prognostic markers
Background: Although prognostic biomarkers specific for particular cancers have been discovered, microarray analysis of gene expression profiles, supported by integrative analysis...
Xinan Yang, Xiao Sun
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BMCBI
2007
97views more  BMCBI 2007»
15 years 2 months ago
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
BMCBI
2007
132views more  BMCBI 2007»
15 years 2 months ago
On the analysis of glycomics mass spectrometry data via the regularized area under the ROC curve
Background: Novel molecular and statistical methods are in rising demand for disease diagnosis and prognosis with the help of recent advanced biotechnology. High-resolution mass s...
Jingjing Ye, Hao Liu, Crystal Kirmiz, Carlito B. L...
BMCBI
2008
136views more  BMCBI 2008»
15 years 2 months ago
Allowing for mandatory covariates in boosting estimation of sparse high-dimensional survival models
Background: When predictive survival models are built from high-dimensional data, there are often additional covariates, such as clinical scores, that by all means have to be incl...
Harald Binder, Martin Schumacher
BMCBI
2007
113views more  BMCBI 2007»
15 years 2 months ago
In silico panning for a non-competitive peptide inhibitor
Background: Peptide ligands have tremendous therapeutic potential as efficacious drugs. Currently, more than 40 peptides are available in the market for a drug. However, since cos...
Yukiko Yagi, Kotaro Terada, Takahisa Noma, Kazunor...
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