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» Improved Phylogenetic Motif Detection Using Parsimony
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BMCBI
2007
141views more  BMCBI 2007»
13 years 7 months ago
HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Erik Larsson, Per Lindahl, Petter Mostad
BMCBI
2010
86views more  BMCBI 2010»
13 years 7 months ago
Fast motif recognition via application of statistical thresholds
Background: Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites...
Christina Boucher, James King
ALMOB
2006
155views more  ALMOB 2006»
13 years 7 months ago
Refining motifs by improving information content scores using neighborhood profile search
The main goal of the motif finding problem is to detect novel, over-represented unknown signals in a set of sequences (e.g. transcription factor binding sites in a genome). The mo...
Chandan K. Reddy, Yao-Chung Weng, Hsiao-Dong Chian...
CCECE
2006
IEEE
14 years 1 months ago
Dynamic and Parallel Approaches to Optimal Evolutionary Tree Construction
Phylogenetic trees are commonly reconstructed based on hard optimization problems such as Maximum parsimony (MP) and Maximum likelihood (ML). Conventional MP heuristics for produc...
Anupam Bhattacharjee, Kazi Zakia Sultana, Zalia Sh...
ISAAC
2004
Springer
115views Algorithms» more  ISAAC 2004»
14 years 25 days ago
Randomized Algorithms for Motif Detection
Motivation: Motif detection for DNA sequences has many important applications in biological studies, e.g., locating binding sites and regulatory signals, and designing genetic prob...
Lusheng Wang, Liang Dong, Hui Fan