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BMCBI
2008
105views more  BMCBI 2008»
13 years 10 months ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...
BMCBI
2008
111views more  BMCBI 2008»
13 years 10 months ago
Probabilistic base calling of Solexa sequencing data
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
Jacques Rougemont, Arnaud Amzallag, Christian Isel...
BMCBI
2006
152views more  BMCBI 2006»
13 years 10 months ago
Amplification of the Gene Ontology annotation of Affymetrix probe sets
Background: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete a...
Enrique M. Muro, Carolina Perez-Iratxeta, Miguel A...
CORR
2007
Springer
95views Education» more  CORR 2007»
13 years 9 months ago
Scheduling in Data Intensive and Network Aware (DIANA) Grid Environments
In Grids scheduling decisions are often made on the basis of jobs being either data or computation intensive: in data intensive situations jobs may be pushed to the data and in co...
Richard McClatchey, Ashiq Anjum, Heinz Stockinger,...
BMCBI
2005
117views more  BMCBI 2005»
13 years 9 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai