Sciweavers

34 search results - page 3 / 7
» Improved benchmarks for computational motif discovery
Sort
View
BMCBI
2006
103views more  BMCBI 2006»
13 years 7 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...
BMCBI
2007
144views more  BMCBI 2007»
13 years 7 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
JCB
2008
159views more  JCB 2008»
13 years 7 months ago
BayesMD: Flexible Biological Modeling for Motif Discovery
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
Man-Hung Eric Tang, Anders Krogh, Ole Winther
ALMOB
2006
102views more  ALMOB 2006»
13 years 7 months ago
Mining, compressing and classifying with extensible motifs
Background: Motif patterns of maximal saturation emerged originally in contexts of pattern discovery in biomolecular sequences and have recently proven a valuable notion also in t...
Alberto Apostolico, Matteo Comin, Laxmi Parida
BMCBI
2006
113views more  BMCBI 2006»
13 years 7 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida