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BMCBI
2010
65views more  BMCBI 2010»
13 years 10 months ago
VIPR: A probabilistic algorithm for analysis of microbial detection microarrays
Background: All infectious disease oriented clinical diagnostic assays in use today focus on detecting the presence of a single, well defined target agent or a set of agents. In r...
Adam F. Allred, Guang Wu, Tuya Wulan, Kael F. Fisc...
BMCBI
2010
128views more  BMCBI 2010»
13 years 10 months ago
VIGOR, an annotation program for small viral genomes
Background: The decrease in cost for sequencing and improvement in technologies has made it easier and more common for the re-sequencing of large genomes as well as parallel seque...
Shiliang Wang, Jaideep P. Sundaram, David Spiro
BMCBI
2007
147views more  BMCBI 2007»
13 years 10 months ago
MaxAlign: maximizing usable data in an alignment
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
Rodrigo Gouveia-Oliveira, Peter Wad Sackett, Ander...
BMCBI
2010
145views more  BMCBI 2010»
13 years 10 months ago
Clustering metagenomic sequences with interpolated Markov models
Background: Sequencing of environmental DNA (often called metagenomics) has shown tremendous potential to uncover the vast number of unknown microbes that cannot be cultured and s...
David R. Kelley, Steven L. Salzberg
BMCBI
2007
147views more  BMCBI 2007»
13 years 10 months ago
Statistical analysis and significance testing of serial analysis of gene expression data using a Poisson mixture model
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...
Scott D. Zuyderduyn
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