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BMCBI
2007
13 years 11 months ago
2007
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
BMCBI
2010
13 years 11 months ago
2010
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
BMCBI
2008
13 years 11 months ago
2008
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...
BMCBI
2007
13 years 11 months ago
2007
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
BMCBI
2007
13 years 11 months ago
2007
Background: A microarray study may select different differentially expressed gene sets because of different selection criteria. For example, the fold-change and p-value are two co...