Background: Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique ha...
We describe a new method to predict the tertiary structure of new-fold proteins. Our two-phase approach combines the knowledge-based fragmentpacking with the minimization of a phy...
Jinhui Ding, Elizabeth Eskow, Nelson L. Max, Silvi...
Abstract: We present a method for simultaneous three-dimensional (3D) structure generation and pharmacophorebased alignment using a self-organizing algorithm called Stochastic Prox...
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...