Background: The accurate detection of differentially expressed (DE) genes has become a central task in microarray analysis. Unfortunately, the noise level and experimental variabi...
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
Johannes Tuikkala, Laura Elo, Olli Nevalainen, Ter...
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...