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» Improving gene set analysis of microarray data by SAM-GS
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BMCBI
2007
107views more  BMCBI 2007»
13 years 7 months ago
Linking microarray reporters with protein functions
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
DAWAK
2005
Springer
14 years 1 months ago
Gene Expression Biclustering Using Random Walk Strategies
A biclustering algorithm, based on a greedy technique and enriched with a local search strategy to escape poor local minima, is proposed. The algorithm starts with an initial rando...
Fabrizio Angiulli, Clara Pizzuti
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Biologically relevant effects of mRNA amplification on gene expression profiles
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...
RECOMB
2008
Springer
14 years 8 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir
TCBB
2008
107views more  TCBB 2008»
13 years 7 months ago
Coclustering of Human Cancer Microarrays Using Minimum Sum-Squared Residue Coclustering
It is a consensus in microarray analysis that identifying potential local patterns, characterized by coherent groups of genes and conditions, may shed light on the discovery of pre...
Hyuk Cho, Inderjit S. Dhillon