Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
A biclustering algorithm, based on a greedy technique and enriched with a local search strategy to escape poor local minima, is proposed. The algorithm starts with an initial rando...
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
It is a consensus in microarray analysis that identifying potential local patterns, characterized by coherent groups of genes and conditions, may shed light on the discovery of pre...