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BMCBI
2007
13 years 10 months ago
2007
Background: Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remain...
BMCBI
2007
2007
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
13 years 10 months ago
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...
BMCBI
2007
13 years 10 months ago
2007
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
BMCBI
2007
13 years 10 months ago
2007
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
BMCBI
2008
13 years 10 months ago
2008
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...