197 search results - page 4 / 40 » Improving pairwise sequence alignment accuracy using near-op... |
RECOMB
2009
Springer
14 years 8 months ago
2009
Springer
Abstract. Accurate comparative analysis tools for low-homology proteins remains a difficult challenge in computational biology, especially sequence alignment and consensus folding ...
NAR
2007
13 years 7 months ago
2007
Multiple sequence alignments are essential in homology inference, structure modeling, functional prediction and phylogenetic analysis. We developed a web server that constructs mu...
RECOMB
2012
Springer
11 years 9 months ago
2012
Springer
We develop a novel and general approach to estimating the accuracy of protein multiple sequence alignments without knowledge of a reference alignment, and use our approach to addre...
BMCBI
2008
13 years 7 months ago
2008
Background: Identification of RNA homologs within genomic stretches is difficult when pairwise sequence identity is low or unalignable flanking residues are present. In both cases...
BMCBI
2005
13 years 7 months ago
2005
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...