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BMCBI
2004
146views more  BMCBI 2004»
13 years 7 months ago
Multivariate search for differentially expressed gene combinations
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...
BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
Very Important Pool (VIP) genes - an application for microarray-based molecular signatures
Background: Advances in DNA microarray technology portend that molecular signatures from which microarray will eventually be used in clinical environments and personalized medicin...
Zhenqiang Su, Huixiao Hong, Hong Fang, Leming M. S...
BMCBI
2008
104views more  BMCBI 2008»
13 years 7 months ago
Missing value imputation improves clustering and interpretation of gene expression microarray data
Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
Johannes Tuikkala, Laura Elo, Olli Nevalainen, Ter...
JCB
2002
160views more  JCB 2002»
13 years 7 months ago
Inference from Clustering with Application to Gene-Expression Microarrays
There are many algorithms to cluster sample data points based on nearness or a similarity measure. Often the implication is that points in different clusters come from different u...
Edward R. Dougherty, Junior Barrera, Marcel Brun, ...
GECCO
2003
Springer
127views Optimization» more  GECCO 2003»
14 years 25 days ago
Complex Function Sets Improve Symbolic Discriminant Analysis of Microarray Data
Abstract. Our ability to simultaneously measure the expression levels of thousands of genes in biological samples is providing important new opportunities for improving the diagnos...
David M. Reif, Bill C. White, Nancy Olsen, Thomas ...