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» In Praise of Numerical Computation
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BMCBI
2010
115views more  BMCBI 2010»
13 years 9 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2007
161views more  BMCBI 2007»
13 years 9 months ago
Efficient classification of complete parameter regions based on semidefinite programming
Background: Current approaches to parameter estimation are often inappropriate or inconvenient for the modelling of complex biological systems. For systems described by nonlinear ...
Lars Kuepfer, Uwe Sauer, Pablo A. Parrilo
BMCBI
2008
130views more  BMCBI 2008»
13 years 9 months ago
FAF-Drugs2: Free ADME/tox filtering tool to assist drug discovery and chemical biology projects
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...
David Lagorce, Olivier Sperandio, Hervé Gal...
CORR
2010
Springer
210views Education» more  CORR 2010»
13 years 9 months ago
Exploiting Statistical Dependencies in Sparse Representations for Signal Recovery
Signal modeling lies at the core of numerous signal and image processing applications. A recent approach that has drawn considerable attention is sparse representation modeling, in...
Tomer Faktor, Yonina C. Eldar, Michael Elad
EOR
2010
88views more  EOR 2010»
13 years 9 months ago
Mathematical programming approaches for generating p-efficient points
Abstract: Probabilistically constrained problems, in which the random variables are finitely distributed, are nonconvex in general and hard to solve. The p-efficiency concept has b...
Miguel A. Lejeune, Nilay Noyan