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ICDE
2010
IEEE
189views Database» more  ICDE 2010»
13 years 7 months ago
Caching all plans with just one optimizer call
Abstract— Modern database management systems (DBMS) answer a multitude of complex queries on increasingly larger datasets. Given the complexities of the queries and the numerous ...
Debabrata Dash, Ioannis Alagiannis, Cristina Maier...
BMCBI
2008
117views more  BMCBI 2008»
13 years 7 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
Whole genome association mapping by incompatibilities and local perfect phylogenies
Background: With current technology, vast amounts of data can be cheaply and efficiently produced in association studies, and to prevent data analysis to become the bottleneck of ...
Thomas Mailund, Søren Besenbacher, Mikkel H...
BMCBI
2007
107views more  BMCBI 2007»
13 years 7 months ago
A computational approach for detecting peptidases and their specific inhibitors at the genome level
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...
Lisa Bartoli, Remo Calabrese, Piero Fariselli, Dam...