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BMCBI
2010
13 years 7 months ago
2010
Background: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due t...
BMCBI
2010
13 years 7 months ago
2010
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
BMCBI
2007
13 years 7 months ago
2007
Background: The identification of transcription factors (TFs) associated with a biological process is fundamental to understanding its regulatory mechanisms. From microarray data,...
BMCBI
2010
13 years 7 months ago
2010
Background: The amount of available biological information is rapidly increasing and the focus of biological research has moved from single components to networks and even larger ...
BMCBI
2008
13 years 7 months ago
2008
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...