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Publication
Non-negative matrix factorization (NMF) has become a standard tool in data mining, information retrieval, and signal processing. It is used to factorize a non-negative data matrix ...
BMCBI
2007
13 years 8 months ago
2007
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
JCB
2007
13 years 7 months ago
2007
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
BMCBI
2011
13 years 2 months ago
2011
Background: The PathOlogist is a new tool designed to transform large sets of gene expression data into quantitative descriptors of pathway-level behavior. The tool aims to provid...
BMCBI
2010
13 years 8 months ago
2010
Background: Pathways in biological system often cooperate with each other to function. Changes of interactions among pathways tightly associate with alterations in the properties ...