Background: The search for cluster structure in microarray datasets is a base problem for the so-called “-omic sciences”. A difficult problem in clustering is how to handle da...
Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
Johannes Tuikkala, Laura Elo, Olli Nevalainen, Ter...
To microarray expression data analysis, it is well accepted that biological knowledge-guided clustering techniques show more advantages than pure mathematical techniques. In this ...
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
Microarray datasets are often too large to visualise due to the high dimensionality. The self-organising map has been found useful to analyse massive complex datasets. It can be us...