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BMCBI
2011
12 years 11 months ago
Clustering gene expression data with a penalized graph-based metric
Background: The search for cluster structure in microarray datasets is a base problem for the so-called “-omic sciences”. A difficult problem in clustering is how to handle da...
Ariel E. Bayá, Pablo M. Granitto
BMCBI
2008
104views more  BMCBI 2008»
13 years 8 months ago
Missing value imputation improves clustering and interpretation of gene expression microarray data
Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
Johannes Tuikkala, Laura Elo, Olli Nevalainen, Ter...
JBI
2006
107views Bioinformatics» more  JBI 2006»
13 years 8 months ago
Knowledge guided analysis of microarray data
To microarray expression data analysis, it is well accepted that biological knowledge-guided clustering techniques show more advantages than pure mathematical techniques. In this ...
Zhuo Fang, Jiong Yang, Yixue Li, Qing-ming Luo, Le...
BMCBI
2007
126views more  BMCBI 2007»
13 years 8 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
IDEAL
2004
Springer
14 years 1 months ago
Visualisation of Distributions and Clusters Using ViSOMs on Gene Expression Data
Microarray datasets are often too large to visualise due to the high dimensionality. The self-organising map has been found useful to analyse massive complex datasets. It can be us...
Swapna Sarvesvaran, Hujun Yin