Background: A new paradigm of biological investigation takes advantage of technologies that produce large high throughput datasets, including genome sequences, interactions of pro...
Background: High-throughput experiments, such as with DNA microarrays, typically result in hundreds of genes potentially relevant to the process under study, rendering the interpr...
Rob Jelier, Guido Jenster, Lambert C. J. Dorssers,...
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Clustering of EST data is a method for the non-redundant representation of an organisms transcriptome. During clustering of large amounts of EST data, usually some large clusters ...
Background: Cluster analysis is an important technique for the exploratory analysis of biological data. Such data is often high-dimensional, inherently noisy and contains outliers...
Benjamin Georgi, Ivan Gesteira Costa, Alexander Sc...