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NAR
2002
138views more  NAR 2002»
13 years 7 months ago
The KEGG databases at GenomeNet
The Kyoto Encyclopedia of Genes and Genomes (KEGG) is the primary database resource of the Japanese GenomeNet service (http://www.genome.ad.jp/) for understanding higher order fun...
Minoru Kanehisa, Susumu Goto, Shuichi Kawashima, A...
BMCBI
2006
171views more  BMCBI 2006»
13 years 8 months ago
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
Roel G. W. Verhaak, Frank J. T. Staal, Peter J. M....
BMCBI
2007
97views more  BMCBI 2007»
13 years 8 months ago
A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, hu
Background: The Affymetrix GeneChip technology uses multiple probes per gene to measure its expression level. Individual probe signals can vary widely, which hampers proper interp...
Rudi Alberts, Peter Terpstra, Menno Hardonk, Leoni...
IDA
2003
Springer
14 years 1 months ago
An Iterated Local Search Approach for Minimum Sum-of-Squares Clustering
Abstract. Since minimum sum-of-squares clustering (MSSC) is an NPhard combinatorial optimization problem, applying techniques from global optimization appears to be promising for r...
Peter Merz
BMCBI
2007
107views more  BMCBI 2007»
13 years 8 months ago
Linking microarray reporters with protein functions
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...