Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Clustering algorithms are routinely used in biomedical disciplines, and are a basic tool in bioinformatics. Depending on the task at hand, there are two most popular options, the ...
The task of clustering is to identify classes of similar objects among a set of objects. The definition of similarity varies from one clustering model to another. However, in most ...
Biological data, such as gene expression profiles or protein sequences, is often organized in a hierarchy of classes, where the instances assigned to "nearby" classes in...
The assessment of the reliability of clusters discovered in bio-molecular data is a central issue in several bioinformatics problems. Several methods based on the concept of stabil...