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BMCBI
2010
113views more  BMCBI 2010»
13 years 10 months ago
Efficient protein alignment algorithm for protein search
Background: Proteins show a great variety of 3D conformations, which can be used to infer their evolutionary relationship and to classify them into more general groups; therefore ...
Zaixin Lu, Zhiyu Zhao, Bin Fu
BMCBI
2010
136views more  BMCBI 2010»
13 years 10 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
BMCBI
2007
100views more  BMCBI 2007»
13 years 10 months ago
SBMLeditor: effective creation of models in the Systems Biology Markup Language (SBML)
Background: The need to build a tool to facilitate the quick creation and editing of models encoded in the Systems Biology Markup language (SBML) has been growing with the number ...
Nicolas Rodriguez, Marco Donizelli, Nicolas Le Nov...
BMCBI
2007
131views more  BMCBI 2007»
13 years 10 months ago
FUNC: a package for detecting significant associations between gene sets and ontological annotations
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
Kay Prüfer, Bjoern Muetzel, Hong Hai Do, Gunt...
BMCBI
2010
132views more  BMCBI 2010»
13 years 10 months ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...