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» Incremental Signaling Pathway Modeling by Data Integration
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ICCS
2007
Springer
14 years 26 days ago
A Multiscale, Cell-Based Framework for Modeling Cancer Development
We use a systems approach to develop a predictive model that medical researchers can use to study and treat cancerous tumors. Our multiscale, cell-based model includes intracellula...
Yi Jiang
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
14 years 5 hour ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
BMCBI
2007
176views more  BMCBI 2007»
13 years 6 months ago
Genome Expression Pathway Analysis Tool - Analysis and visualization of microarray gene expression data under genomic, proteomic
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...
Markus Weniger, Julia C. Engelmann, Jörg Schu...
ITNG
2008
IEEE
14 years 1 months ago
GlycoVault: A Bioinformatics Infrastructure for Glycan Pathway Visualization, Analysis and Modeling
Glycan biosynthesis is the process by which glycans are built in the cells. Information about the process is available from several Web accessible databases, published papers, exp...
Shravya Nimmagadda, Amrita Basu, Matthew Eavenson,...
BMCBI
2006
133views more  BMCBI 2006»
13 years 6 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...