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BMCBI
2010
191views more  BMCBI 2010»
13 years 9 months ago
Colonyzer: automated quantification of micro-organism growth characteristics on solid agar
Background: High-throughput screens comparing growth rates of arrays of distinct micro-organism cultures on solid agar are useful, rapid methods of quantifying genetic interaction...
Conor Lawless, Darren J. Wilkinson, Alexander Youn...
BMCBI
2010
118views more  BMCBI 2010»
13 years 9 months ago
Bacillus anthracis genome organization in light of whole transcriptome sequencing
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...
Jeffrey Martin, Wenhan Zhu, Karla D. Passalacqua, ...
BMCBI
2007
146views more  BMCBI 2007»
13 years 9 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2008
144views more  BMCBI 2008»
13 years 9 months ago
WGCNA: an R package for weighted correlation network analysis
Background: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method ...
Peter Langfelder, Steve Horvath
BMCBI
2008
140views more  BMCBI 2008»
13 years 9 months ago
Improved accuracy of multiple ncRNA alignment by incorporating structural information into a MAFFT-based framework
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...
Kazutaka Katoh, Hiroyuki Toh